Effects of Endurance Exercise on Cerebral and Muscle Oxygenation

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dc.contributor.advisor Neary, Patrick
dc.contributor.author Duff, Whitney Ranelle Dorthy
dc.date.accessioned 2012-11-23T21:32:18Z
dc.date.available 2012-11-23T21:32:18Z
dc.date.issued 2012-07
dc.identifier.uri http://hdl.handle.net/10294/3646
dc.description A Thesis Submitted to the Faculty of Graduate Studies and Research In Partial Fulfillment of the Requirements for the Degree of Master of Science in Kinesiology and Health Studies, University of Regina. xii, 111 l. en_US
dc.description.abstract It has been suggested that during exhaustive exercise both a central and peripheral mechanism of fatigue exists. Indeed, a central debate in the exercise science literature is the nature of fatigue that determines exercise performance under different conditions (Swart et al., 2009a). Hypoxia, for example, has a small but direct role on the cessation of exercise, specifically during endurance performances (Millet, Aubert, Favier, Busso, & Benoit, 2008; Secher, Seifert, & Van Lieshout, 2008). Numerous studies to date have provided new information related to the factors implicated in short-term high intensity exercise, while more studies of a longer nature (endurance time trials), measuring central and peripheral fatigue factors simultaneously, and under hypoxic conditions, are needed to add additional information to guide our understanding of the mechanisms involved in central and peripheral fatigue. This thesis represents a contribution to the much needed research within this area. Four key papers, separated into four chapters, discuss this research in this thesis. To investigate these effects, an integrative physiological approach was used by including muscle and cerebral oxygenation changes (NIRS), cardiovascular and pulmonary responses and blood biochemistry during cycling exercise in a normoxic and hypoxic environment. The primary inference of this thesis is that in hypoxia the brain is protected and the muscle is in need of a similar oxygenation and extraction to do less work; a finding that contributes to the support of previous speculations in the literature. A secondary inference of this thesis is that a difference in the pattern of oxygenation between continuous and incremental exercise exists; a finding that has not been previously identified in the literature. The findings from this study have therefore furthered our understanding of the nature of fatigue, specifically in endurance exercise under acute hypoxic conditions, and the relationship between the central and peripheral factors associated with fatigue. en_US
dc.language.iso en en_US
dc.publisher Faculty of Graduate Studies and Research, University of Regina en_US
dc.subject.lcsh Exercise--Physiological aspects
dc.subject.lcsh Cerebral anoxia
dc.subject.lcsh Muscles--Physiology
dc.subject.lcsh Oxygen--Physiological transport
dc.subject.lcsh Oxygen in the body
dc.subject.lcsh Fatigue
dc.title Effects of Endurance Exercise on Cerebral and Muscle Oxygenation en_US
dc.type Thesis en
dc.description.authorstatus Student en
dc.description.peerreview yes en
thesis.degree.name Master of Science (MSc) en_US
thesis.degree.level Master's en
thesis.degree.discipline Kinesiology en_US
thesis.degree.grantor University of Regina en
thesis.degree.department Faculty of Kinesiology and Health Studies en_US
dc.contributor.committeemember Candow, Darren
dc.contributor.committeemember Somers, Christopher
dc.contributor.externalexaminer Billaut, Francois
dc.identifier.tcnumber TC-SRU-3646
dc.identifier.thesisurl http://ourspace.uregina.ca/bitstream/handle/10294/3646/Duff_Whitney_200242660_MSC_KHS_Fall_2012.pdf

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