Social anxiety disorder (SAD) is characterized by intense fear or anxiety in response to social situations (APA, 2013). Individuals with SAD experience clinically significant distress and impairment and, if left untreated, the disorder typically follows a chronic and unremitting course (APA, 2013; Hofmann, Heinrichs, & Moscovitch, 2004). Intolerance of uncertainty (IU) is “an individual’s dispositional incapacity to endure the aversive response triggered by the perceived absence of salient, key, or sufficient information, and sustained by the associated perception of uncertainty” (Carleton, 2016, p.31). Several studies have implicated high IU as a potential risk factor underlying the development and maintenance of various anxiety and mood disorders, including SAD (see for review, Carleton, 2012; 2016; in press). Previous studies have implicated high IU as being detrimental to decision-making processes and adaptive responses (Jensen, Kind, Morrison, & Heimberg, 2014; Luhmann, Ishida, & Hajcak, 2011); however, research to date has not examined the relationship between IU and decision-making within disorder-specific contexts, except within the context of generalized anxiety disorder. Further, little research has examined the relationship between IU and anxiety under threat (e.g., Reuman, Jacoby, Fabricant, Herring, & Abramowitz, 2014). The current investigation was designed to examine the relationship between IU and social anxiety symptoms by assessing the impact of social threat and IU on decision-making. Undergraduate participants (n = 106, 81% women) with diverse levels of baseline, self-reported social anxiety symptoms were asked to complete two sets of decision-making tasks in either a high social threat condition or a low social threat condition. Correlational, linear regression, and mediational analyses were conducted to characterize decision-making performance across the different groups and conditions, as well as assess the role of IU as a potential mediator of the relationship between decision-making and social anxiety. High self-reported IU and high self-reported social anxiety were both significantly inversely associated with information gathering in the Beads Task, particularly for participants assigned to the high social threat condition. High self-reported IU and high self-reported social anxiety were significantly associated with overall latency in the modified Iowa Gambling Task (MIGT) in the low social threat condition. There was a significant inverse relationship between SAD-specific IU and advantageous play in the MIGT and a trend toward a significant inverse association between SAD-specific IU and disadvantageous play in the MIGT. The results of mediation analyses did not support IU as mediating the relationship between social anxiety and decision-making. The current results were consistent with contemporary models of anxiety positing uncertainty as critical (Carleton, 2012; 2016; in press). Participants exhibited behaviours and decision-making outcomes consistent with the notion that uncertainty reduction is a primary implicit goal in individuals high in IU and anxiety, particularly when faced with fear-relevant contexts. The current results also help elucidate posited differences in the influence of inhibitory and prospective IU on decision-making processes in domain-specific environments (i.e., socially anxious individuals faced with a socially threatening situation). Further, the results support the utility of and need for additional research examining the role of disorder-specific IU. A better understanding of the role of IU in decision-making within disorder-specific contexts can be used to inform treatment interventions targeting IU reduction and improve treatment outcomes.